Tweetree is an alternative to the web interface at Twitter.com featuring expanded URLs and threaded conversations. Aside from those features, it sports a web interface whose primary difference from twitter.com is skin deep.
Tweetree handles all of the common Twitter streams & features like home, @ mentions, direct messages, and favorites. It has basic search and lets you save your common searches. It has a handy button for retweeting as well.
Readtwit is a web service that finds links in your Twitter stream and formats them as an RSS feed. You may be saying "hold on here, I can get an RSS feed of my tweets from Twitter.com" but Readtwit has some goodies that make it a worthwhile service.
First of all, it only loads tweets with links in them. Tweets with no links will get skipped, so if you're not a fan of chatty banter, this will appeal to you.
GeoChirp lets you keep track of people tweeting in any local region. This mashup was created by combining Google Maps and Twitter.
pic.im is an image uploading service offering integration with tr.im and Nambu. All three are part of the Nambu Network, and as a result play nice together.
You can download the pic.im app to upload pictures on your iPhone. You can just as easily share images from your desktop using Nambu. Both show you some basic statistics about the photos in your pic.im account.
Nomee collects many social networks, allowing you to focus on following people instead of websites. It tracks a huge number of social networks. Nomee does not cater to any one social network extensively, including Twitter. Still, it seemed appropriate to write up its actual tweeting abilities for those curious about using this social dashboard.
Nambu is a feature-rich Twitter app for Mac OS X that supports many social networks. It offers plenty of configuration options but has simple defaults for beginners. It also has excellent integration with its sister services, tr.im and pic.im
DestroyTwitter is a full-featured yet lightweight Adobe AIR twitter app. While many other AIR apps are guilty of being on the pudgy and/or sluggish side, DestroyTwitter is refreshingly responsive. Upon load it starts at about 40MB and after using it for a bit, searching, and loading a couple other columns it only climbed to 61MB. Very good for an AIR app!
Even though the memory footprint is light, it doesn't skimp on features. The app is maintained by Jonnie Hallman, an Experience Designer at Adobe, so that may have something to do with it.
Twalala is a simple web application with some stream filtering so you can control what you see, and what you don't want to see. If their name confuses you, think of a kid sticking his fingers in his ears and saying "lalala!" to block out what someone else is saying. From their website:
Get ready to take control of your twitterstream. twalala is a client for Twitter that allows you to control what you see, and more importantly, what you don't see in your twitterstream...
Finally, Twitter with a mute button.
Tweetie is a gorgeous, full-featured desktop Twitter client for Macintosh. atebits is the company behind Tweetie, already known for the fantastic iPhone version of Tweetie. Notable features include:
Twitter Analyzer is a web app that provides granular twitter analytics for any user. They bill themselves as "Twitter Analyzer Is The Most Advanced Twitter Analytic System In The World." It has a vast selection of options for viewing your twitter data. It is simple to get started; you enter your username. It thinks for a while, then loads daily graphs of your data filtered many ways: